Umiatin, Ismail Hadisoebroto Dilogo, Sastra Kusuma Wijaya, Puji Sari, Andika Dwiputra Djaja
This study aims to design and develop the pulsed electromagnetic fields (PEMF) device which can be utilized as an adjuvant therapy in delayed union fracture. In the first stage, Arduino-based PEMF device has been built with four main modules: pulse generator, user interface, Helmholtz coil and data acquisition system. Pulse generator allowing user to operate the physical parameters: frequency, duty cycle, burst duration and exposure duration. The Helmholtz coil could produce 1.6 mT of homogenous magnetic field. In the next stage, preliminary study was done to evaluate the effect of static magnetic field (SMF) and PEMF exposure on the healing of delayed union fracture model on Spraque Dawley (SD) rats. Six SD rats were fracturized at the femoral shaft by non-union model, then they were grouped into 2 groups, 1 (n = 3, SMFexposure, Bmax = 1.6 mT) and 2 (n = 3, PEMF exposure, Bmax = 1.6 mT frequency = 50Hz, duty cycle = 90%, burst cycle = 50%). Both groups had received the exposure for 4 hours per day and 7 hours per week. The evaluations of fracture healing were conducted by the histomorphometry analysis at 14, 21, and 28 days fracturization. PEMF group signal a better healing process through higher osseous tissue area. © 2019 Author(s).
Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia; Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Pulo Gadung, East Jakarta, Jakarta, 13220, Indonesia; Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia; Department of Physics, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Department of Biology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia
Research at a Glance
Register to unlock
Topics & SDG Alignment
Register to unlock
Collaboration
Register to unlock
Author Profile (Selected)
Register to unlock
References Overview
Register to unlock
Journal & Source
Register to unlock
Metadata & Integrity
Register to unlock